Daniel Lopez

Graduate Student

Biochemistry & Cellular and Molecular Biology

E-mail: dlopez7@vols.utk.edu

Education & Training

B.S.   Biological Sciences, The University of Tennessee, Knoxville.

Emergency Medical Technician, Roane State.


Bio

During my undergrad I worked in Dr. Tongye Shen’s lab where I performed different computational methods to study and understand various molecular/cellular biosystems and cellular dynamics. I specifically looked at the protein-ligand interactions of nuclear hormone receptors to gain insight into the constitutive activity of certain receptors. I am interested in applying machine learning/deep learning to -omic data to help solve complex problems. In my free time, I enjoy spending time with my friends, working out and playing guitar and piano.

 


Publications

Lopez D, Tyson DR, Hong T. Intercellular signaling reinforces single-cell level phenotypic transitions and facilitates robust re-equilibrium of heterogeneous cancer cell populations. Cell Commun Signal 2025; 23(1):386 [Link] [Article]

Pham B, Cheng Z, Lopez D, Lindsay RJ, Foutch D, Majors RT, Shen T. Statistical Analysis of Protein-Ligand Interaction Patterns in Nuclear Receptor RORγ. Front Mol Biosci 2022; 9

Harnish MT, Lopez D, Morrison CT, Narayanan R, Fernandez EJ, Shen T. SNovel Covalent Modifier-Induced Local Conformational Changes within the Intrinsically Disordered Region of the Androgen Receptor. Biology 2023; 12 (11), 1442